Related Experiment Video
Updated: Mar 2, 2026
08:46
Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis
Published on: September 16, 2014
8.2K
A Versatile Electronic Tongue Based on Surface Plasmon Resonance Imaging and Cross-Reactive Sensor Arrays-A
Laurie-Amandine Garçon1,2,3,4, Maria Genua5,6,7, Yanjie Hou8,9,10
1Institut Nanosciences et Cryogénie, University of Grenoble Alpes, INAC-SyMMES, F-38000 Grenoble, France. laurie-amandine.garcon@hotmail.fr.
Sensors (Basel, Switzerland)
|May 9, 2017
Summary
A new versatile electronic tongue (eT) system combines surface plasmon resonance imaging (SPRi) with combinatorial chemistry for diverse sample analysis. This innovative multisensor approach generates kinetic data for classifying complex mixtures and differentiating protein isoforms.
Area of Science:
- Analytical Chemistry
- Biosensor Technology
- Materials Science
Background:
- Growing demand for advanced analytical devices to enhance daily life quality.
- Multisensor systems, particularly electronic tongues (eTs), offer promising solutions.
- Need for simplified yet diverse sensing material preparation.
Purpose of the Study:
- To develop a versatile electronic tongue (eT) system.
- To simplify the creation of diverse sensing materials using a combinatorial approach.
- To demonstrate the system's capability in analyzing complex samples and generating kinetic information.
Main Methods:
- Coupling surface plasmon resonance imaging (SPRi) with cross-reactive sensor arrays.
- Employing an innovative combinatorial approach by mixing small, accessible molecules.
- Generating 2D continuous evolution profiles (CEP) and 3D continuous evolution landscapes (CEL).
Main Results:
- Successful differentiation of protein isoforms, such as chemokines CXCL12α and CXCL12γ.
- Effective analysis of complex mixtures, exemplified by milk samples.
- Demonstrated potential for monitoring milk deterioration using kinetic data.
Conclusions:
- The developed SPRi-based eT system offers a versatile platform for diverse analytical applications.
- The combinatorial approach simplifies sensing material preparation, enabling broad applicability.
- The system provides valuable kinetic information for sample classification and monitoring.
