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Spontaneous resolution of hypercalcemia.

Emily N Ahadizadeh1, Nauman F Manzoor2, Jay Wasman3

  • 1Ear, Nose, and Throat Institute, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, LKS 4500, Cleveland, OH, United States; Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH, United States.

American Journal of Otolaryngology
|May 10, 2017
PubMed
Summary

A case of primary hyperparathyroidism (PHPT) resolved spontaneously due to parathyroid gland infarction. This highlights the need for further investigation of fluctuating electrolyte levels.

Keywords:
HyperparathyroidismInfarctionOtorhinolaryngologyParathyroidParathyroidectomy

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Area of Science:

  • Endocrinology
  • Pathology

Background:

  • Primary hyperparathyroidism (PHPT) is a common endocrine disorder often diagnosed incidentally due to hypercalcemia.
  • It is typically caused by neoplastic lesions or hyperplasia of the parathyroid glands.

Observation:

  • A 55-year-old male presented with a neck mass and electrolyte abnormalities indicative of PHPT.
  • Remarkably, his laboratory values normalized spontaneously before surgical intervention.

Findings:

  • Post-operative pathological examination revealed massive infarction of the affected parathyroid gland.
  • This infarction explained the spontaneous resolution of the patient's electrolyte imbalances.

Implications:

  • This case underscores the importance of investigating fluctuating laboratory values in patients with suspected PHPT.
  • It also highlights the potential risks associated with parathyroid gland infarction and its impact on endocrine disorders.