Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Metabolism01:19

Regulation of Metabolism

11.9K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
11.9K
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

53
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
53
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

6.1K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Lactarius deliciosus</i> Extract from Green Microwave-Assisted Eutectic Solvent Extraction as a Therapeutic Candidate Against Colon Cancer.

Antioxidants (Basel, Switzerland)·2025
Same author

The Disruption of <i>Cyp7b1</i> Controls IGFBP2 and Prediabetes Exerted Through Different Hydroxycholesterol Metabolites.

International journal of molecular sciences·2025
Same author

Antimicrobial Activity and Potential of Olive Leaf Extract as a Topical Agent to Combat <i>Staphylococcus aureus</i> and MRSA Strains: An In Vitro Evaluation.

Pharmaceuticals (Basel, Switzerland)·2025
Same author

Effect of Extra Virgin Olive Oil High in Bioactive Compounds on Atherosclerosis in Apoe-Deficient Mice.

Molecular nutrition & food research·2025
Same author

Chitosan Nanoparticles, a Novel Drug Delivery System to Transfer Squalene for Hepatocyte Stress Protection.

ACS omega·2025
Same author

Squalene in Nanoparticles Improves Antiproliferative Effect on Human Colon Carcinoma Cells Through Apoptosis by Disturbances in Redox Balance.

International journal of molecular sciences·2024

Related Experiment Video

Updated: Mar 2, 2026

Lipidomics and Transcriptomics in Neurological Diseases
09:58

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

4.1K

Transcriptomics and the Mediterranean Diet: A Systematic Review.

Luis V Herrera-Marcos1,2, José M Lou-Bonafonte3,4,5, Carmen Arnal6,7,8

  • 1Departamento de Bioquímicay Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón-Universidad de Zaragoza, E-50013 Zaragoza, Spain. l.vte.herrera@gmail.com.

Nutrients
|May 10, 2017
PubMed
Summary

The Mediterranean diet impacts gene expression across tissues, influencing health outcomes. Virgin olive oil compounds, like phenols, show promise in modulating inflammatory and circadian genes.

Keywords:
Mediterranean dietgene expression profilemicroarrayolive oiltranscriptome

More Related Videos

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
07:25

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans

Published on: December 9, 2022

2.1K
The MPLEx Protocol for Multi-omic Analyses of Soil Samples
10:12

The MPLEx Protocol for Multi-omic Analyses of Soil Samples

Published on: May 30, 2018

11.8K

Related Experiment Videos

Last Updated: Mar 2, 2026

Lipidomics and Transcriptomics in Neurological Diseases
09:58

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

4.1K
Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
07:25

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans

Published on: December 9, 2022

2.1K
The MPLEx Protocol for Multi-omic Analyses of Soil Samples
10:12

The MPLEx Protocol for Multi-omic Analyses of Soil Samples

Published on: May 30, 2018

11.8K

Area of Science:

  • Nutritional Genomics
  • Molecular Biology
  • Dietary Interventions

Background:

  • The Mediterranean diet is linked to reduced cardiovascular disease, cancer, and mortality.
  • Transcriptomics, particularly non-coding RNAs, plays a role in biological regulation.
  • Understanding dietary impacts on gene expression is crucial for health.

Purpose of the Study:

  • To systematically review evidence on the Mediterranean diet's influence on tissue transcriptomes.
  • To explore the role of regulatory RNAs in diet-mediated effects.
  • To investigate the specific effects of virgin olive oil components on gene expression.

Main Methods:

  • Systematic literature review of experimental models.
  • Analysis of transcriptomic data related to Mediterranean diet components.
  • Focus on virgin olive oil's oily matrix and phenolic compounds.

Main Results:

  • Mediterranean diet influences transcriptomes across various tissues and organisms.
  • Monounsaturated fatty acid-rich diets and olive oil phenols inhibit inflammatory gene expression.
  • Specific compounds like tyrosol, hydroxytyrosol, and oleanolic acid modulate cell cycle and circadian clock genes.

Conclusions:

  • The Mediterranean diet exerts universal effects on gene expression, with tissue-specific variations.
  • Virgin olive oil components are key mediators of these transcriptomic changes.
  • Further research into regulatory RNAs and specific compounds is warranted.