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Analyses of Ferrous and Ferric State in DynabiTab Using Mössbauer Spectroscopy
Young Rang Uhm1, Jae Cheong Lim1, Sang Mu Choi1
1Nuclear Materials Research Division, Korea Atomic Energy Research Institute (KAERI), Daejeon 34057, Republic of Korea.
Abstract:
Antianemic medicament ferrous gluconate, ferrous fumarate, and a Dynabi tablet with a basic iron bearing ingredient were studied with the use of Mössbauer spectroscopy. Room temperature spectra of ferrous gluconate gave clear evidence that the two phases of iron were present: ferrous (Fe2+) as a major one with a contribution at and above 91 a.u.% and ferric (Fe3+) whose contribution was found to be ~9 a.u.%. In the case of ferrous fumarate, a single phase was measured corresponding to ferrous (Fe2+) state. A Dynabi tablet consists of ferrous fumarate and ferrous fumarate. The ferric phase in ferrous gluconate is able to be reached about ~3.6 a.u.% in a tablet.
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