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Updated: Mar 2, 2026
2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia
Published on: June 22, 2013
RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
Fang Yu1, Haidong Liang1, Shimeng Xin1
1The Second Hospital of Dalian Medical University, Dalian, China.
Background:
The acute kidney injury (AKI) may do damage to remote organs. Objective of the study is to investigate effect of seaweed extract (SE) on brain oxidative damage in kidney ischemia/reperfusion rats.
Material And Methods:
Animals were randomly divided into five groups. SE pre-fed to rats.
Results:
Kidney I/R may cause oxidative injury in kidneys and brains tissue in rats. SE pre-treatment can decrease lipid peroxidation levels and increase antioxidant enzymes activities in kidney and brain hippocampus of kidney I/R rats.
Conclusion:
Our results indicate that SE is useful for brain nerve function keeping in kidney I/R rats.
