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Development of a Chlorantraniliprole Microcapsule Formulation with a High Loading Content and Controlled-Release
Baoxia Liu1,2, Yan Wang3, Fei Yang1,2
1Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry , Chinese Academy of Sciences , Beijing 100190 , China.
Journal of Agricultural and Food Chemistry
|May 11, 2017
Summary
New porous microcapsules enhance chlorantraniliprole (CAP) pesticide delivery. These stable, sustained-release formulations show superior efficacy against Plutella xylostella, offering a promising alternative to traditional pesticide options.
Area of Science:
- Agricultural Chemistry
- Materials Science
- Pest Management
Background:
- Microcapsule formulations are crucial in agriculture for improving pesticide efficiency and reducing environmental impact.
- Commercial chlorantraniliprole (CAP) formulations are limited by CAP's poor solubility in organic solvents, hindering advanced formulation development.
- Developing novel delivery systems is essential to overcome limitations of existing pesticide formulations.
Purpose of the Study:
- To develop novel microcapsule formulations of chlorantraniliprole (CAP) with high loading content.
- To investigate the stability, release characteristics, and efficacy of the developed CAP microcapsules.
- To explore the potential of porous microcapsules as an advanced delivery system for pesticides.
Main Methods:
- Utilized a solid in oil in water (S/O/W) double-emulsion method combined with premix membrane emulsion.
- Constructed porous microcapsules by tuning surface porosity and size.
- Evaluated microcapsule properties including light and thermal stability, and release kinetics.
- Conducted bioassays against Plutella xylostella to compare efficacy with commercial formulations.
Main Results:
- Successfully constructed CAP microcapsule formulations with high loading content using the S/O/W double-emulsion and premix membrane emulsion techniques.
- The microcapsules exhibited good light and thermal stability and demonstrated significantly sustained release over a long period.
- Release profiles could be effectively regulated by adjusting the surface porosity and size of the porous microcapsules.
- Bioassays revealed that the porous microcapsule formulations achieved superior control efficacy against Plutella xylostella compared to the commercial formulation.
Conclusions:
- Porous microcapsule delivery systems offer an effective method for formulating poorly soluble pesticides like chlorantraniliprole.
- The developed microcapsules provide enhanced stability and controlled, sustained release, improving pesticide performance.
- This advanced formulation strategy shows significant potential for commercial application in pest management, outperforming traditional formulations.
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