Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

808
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
808
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

440
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
440
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

964
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
964
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

1.4K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.4K
Pancreatic Juice and Secretion01:26

Pancreatic Juice and Secretion

3.3K
Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
3.3K
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

578
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
578

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated Assessment of Skeletal Muscle Quantity and Quality Is Associated with Survival in Patients with Oesophagogastric Malignancies: A Retrospective Cohort Study.

Cancers·2026
Same author

Real-world outcomes of pegcetacoplan treatment in C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis.

Kidney international·2026
Same author

The kidney in the middle: Kidney Disease: Improving Global Outcomes (KDIGO) guidelines address multiple key components of cardiovascular-kidney-metabolic syndrome.

Kidney international·2026
Same author

Kidney Disease: Improving Global Outcomes Green Dialysis Controversies Conference: A Carbon Footprint and Sustainability Report.

Kidney international reports·2026
Same author

Infection risk mitigation with complement inhibitors in kidney disease.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Targeting B cells in immune-mediated kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Kidney international·2026

Related Experiment Video

Updated: Mar 2, 2026

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
06:28

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

443

Enteric hyperoxaluria in chronic pancreatitis.

Nathalie Demoulin1, Zaina Issa, Ralph Crott

  • 1Division of Nephrology, Cliniques universitaires Saint-Luc Institut de Recherche Expérimentale et Clinique Institut de Recherche Santé et Société, Université catholique de Louvain Department of Radiology Department of Clinical Chemistry Department of Hepato-Gastroenterology, Cliniques universitaires Saint-Luc, Brussels, Belgium.

Medicine
|May 11, 2017
PubMed
Summary
This summary is machine-generated.

Hyperoxaluria is common in chronic pancreatitis, linked to steatorrhea and pancreatic damage. This condition accelerates kidney function decline, highlighting a significant link between pancreatic health and renal outcomes.

More Related Videos

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
07:10

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

Published on: April 1, 2022

5.1K
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

4.6K

Related Experiment Videos

Last Updated: Mar 2, 2026

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
06:28

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

443
Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
07:10

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

Published on: April 1, 2022

5.1K
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

4.6K

Area of Science:

  • Nephrology
  • Gastroenterology
  • Internal Medicine

Background:

  • Chronic pancreatitis can cause steatorrhea and kidney damage.
  • The prevalence, determinants, and renal impact of hyperoxaluria in chronic pancreatitis are understudied.

Purpose of the Study:

  • To investigate the prevalence and predictors of hyperoxaluria in chronic pancreatitis patients.
  • To assess the association between hyperoxaluria and renal function decline in this cohort.

Main Methods:

  • Observational study of adult chronic pancreatitis patients.
  • Urine oxalate to creatinine ratio assessed in random urine samples.
  • Comparison of baseline characteristics and annual estimated glomerular filtration rate (eGFR) change between hyper- and normo-oxaluric groups.

Main Results:

  • Hyperoxaluria (urine oxalate to creatinine ratio >32 mg/g) was present in 23% of patients.
  • Independent predictors of hyperoxaluria included clinical steatorrhea, high fecal acid steatocrit (>31%), and pancreatic atrophy.
  • Higher urine oxalate to creatinine ratio was associated with a faster decline in eGFR after adjusting for other risk factors.

Conclusions:

  • Hyperoxaluria is prevalent in chronic pancreatitis and linked to accelerated renal function decline.
  • Clinical steatorrhea, high fecal acid steatocrit, and pancreatic atrophy are key predictors of hyperoxaluria in these patients.
  • Further research is needed to explore renal damage mechanisms and therapeutic strategies for reducing oxaluria.