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[Malignant fibrous histiocytoma].
A Leicher-Düber1, C Düber, M Thelen
1Institut für Klinische Strahlenkunde, Johannes-Gutenberg-Universität Mainz.
Summary
Malignant fibrous histiocytoma (MFH) is a pleomorphic sarcoma. Diagnostic imaging, including radiography, sonography, CT, and angiography, reveals characteristic features of MFH in soft tissue and bone.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Malignant fibrous histiocytoma (MFH) is a pleomorphic sarcoma with ubiquitous origin.
- MFH can affect both soft tissues and bone.
Purpose of the Study:
- To illustrate the clinical and radiological features of MFH.
- To describe the imaging characteristics of MFH in various modalities.
Main Methods:
- Review of 23 cases of soft tissue MFH and 4 cases of bone MFH.
- Analysis of conventional radiography, sonography, CT, and angiography findings.
- Discussion of magnetic resonance tomography (MRT) findings in relevant literature.
Main Results:
- Radiography shows MFH as a soft tissue tumor, potentially involving bone.
- Sonography typically reveals non-homogeneous, hypoechoic masses with necrotic areas.
- CT demonstrates homogeneous or inhomogeneous masses with areas of decreased density and contrast enhancement.
- Angiography indicates hypo- or hypervascularity with pathologic vessels.
Conclusions:
- MFH exhibits distinct imaging features across multiple diagnostic modalities.
- Understanding these features aids in the diagnosis and characterization of MFH.
- Integrated imaging analysis is crucial for comprehensive MFH assessment.