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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Infection associated acute interstitial nephritis; a case report.
Rupesh Raina1, Shirisha Ale1, Tushar Chaturvedi1
1Division of Nephrology, Department of Internal Medicine and Research Cleveland Clinic Akron General, Akron, Ohio, USA.
Acute interstitial nephritis (AIN) is a common cause of acute kidney injury (AKI) often linked to infections. Prompt diagnosis and treatment, potentially including corticosteroids, are crucial for recovery, but infection control is key before immunosuppression.
Area of Science:
- Nephrology
- Pathology
- Infectious Diseases
Background:
- Acute interstitial nephritis (AIN) is a significant cause of acute kidney injury (AKI), frequently under-diagnosed.
- Infection-associated AIN, though less common since antimicrobials, can present with renal insufficiency without classic AIN symptoms.
- Renal biopsy is the definitive diagnostic and prognostic tool for AIN.
Related Concept Videos
Acute Pyelonephritis I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Kidney Injury I: Introduction
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

