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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

616
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
616
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

292
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
292
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

645
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
645
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

388
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
388
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

485
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
485
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

432
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
432

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Related Experiment Video

Updated: Mar 2, 2026

Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
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Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes

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Listeria Endocarditis: A Diagnostic Challenge.

Wilhelmina J A R M Valckx1, Suzanne P M Lutgens1, Hortence E Haerkens-Arends1

  • 1Jeroen Bosch Hospital, Den Bosch, the Netherlands.

Journal of Investigative Medicine High Impact Case Reports
|May 12, 2017
PubMed
Summary

Diagnosing Listeria monocytogenes endocarditis is challenging. An 18F-FDG PET-CT scan aided in identifying infection in a patient with prosthetic valve endocarditis, leading to successful treatment.

Keywords:
18F-FDG PET-CT scanListeria monocytogenesendocarditis

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Nuclear Medicine

Background:

  • Listeria monocytogenes endocarditis is a rare but serious infection, particularly in immunocompromised patients.
  • Prosthetic valve endocarditis presents diagnostic challenges, often requiring advanced imaging.
  • A 74-year-old hemodialysis patient with multiple cardiac interventions developed recurrent fever after initial antibiotic treatment for pneumonia.

Purpose of the Study:

  • To investigate the utility of 18F-FDG PET-CT in diagnosing prosthetic valve endocarditis caused by Listeria monocytogenes.
  • To highlight the diagnostic challenges and successful management of a complex endocarditis case.

Main Methods:

  • Case report of a 74-year-old hemodialysis patient with suspected endocarditis.
  • Utilized transthoracic and transesophageal echocardiography, blood cultures, and 18F-FDG PET-CT imaging.
  • Administered amoxicillin for treatment, with extended duration based on clinical response.

Main Results:

  • Blood cultures confirmed Listeria monocytogenes; initial echocardiography was negative for endocarditis.
  • Recurrent fever post-antibiotics and positive minor Duke criteria prompted 18F-FDG PET-CT.
  • 18F-FDG PET-CT revealed increased activity in the aortic root, ascending aorta, and heart, supporting Listeria monocytogenes endocarditis.
  • Extended amoxicillin therapy resulted in a good clinical outcome.

Conclusions:

  • 18F-FDG PET-CT is a valuable tool for diagnosing challenging cases of prosthetic valve endocarditis, especially when conventional methods are inconclusive.
  • Early and accurate diagnosis of Listeria monocytogenes endocarditis is crucial for effective treatment and patient survival.
  • Multimodality imaging and prolonged antibiotic therapy are essential for managing complex endocarditis cases.