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Related Experiment Video

Updated: Mar 2, 2026

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
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Multiple sclerosis in India: Iceberg or volcano.

Insha Zahoor1, Ehtishamul Haq1

  • 1Department of Biotechnology, University of Kashmir, Srinagar, J&K 190006, India.

Journal of Neuroimmunology
|May 13, 2017
PubMed
Summary

Multiple sclerosis (MS), a neurodegenerative disease, is increasingly recognized in India, challenging its previous low-risk status. Further epidemiological studies are crucial for accurate prevalence data and effective management strategies.

Keywords:
ChallengesEpidemiologicalIndiaMultiple sclerosisPrevalenceScenario

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Area of Science:

  • Neurology
  • Neuroimmunology
  • Epidemiology

Background:

  • Multiple sclerosis (MS) is a chronic neurodegenerative condition affecting the central nervous system.
  • Historically, MS was considered rare in India, primarily affecting Caucasian populations.
  • Recent observations indicate a significant shift in MS prevalence globally and within India.

Purpose of the Study:

  • To provide an overview of the changing landscape of MS in India.
  • To highlight global challenges in MS management.
  • To emphasize the need for updated epidemiological data in India.

Main Methods:

  • This is a review article.
  • It synthesizes existing literature on MS prevalence and trends.
  • It discusses challenges in MS research and management.

Main Results:

  • India is no longer considered a low-risk zone for MS.
  • There is a notable increase in MS cases within the Indian subcontinent.
  • Significant gaps exist in large-scale, population-based epidemiological studies in India.

Conclusions:

  • The perception of MS prevalence in India needs re-evaluation.
  • There is an urgent need for robust epidemiological studies to determine true incidence and prevalence rates.
  • Findings will inform future research and national MS management strategies.