Renal Arterial Mycotic Aneurysm After Kidney Transplantation

Hélène Lazareth1, Maren Burbach1, Clément Gosset2

  • 1Department of Nephrology and Kidney Transplantation, Saint-Louis Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.

Urology
|May 13, 2017
PubMed

Insights

Mycotic aneurysms are rare fungal infections affecting arteries, often seen in kidney transplant recipients. This case highlights a Candida infection in a renal artery aneurysm following transplantation from a donor with a digestive wound.

Area of Science:

  • Medical Mycology
  • Transplant Surgery
  • Vascular Surgery

Background:

  • Mycotic aneurysms are uncommon arterial infections, typically caused by Candida or Aspergillus species.
  • Candida-related arteritis has been documented in approximately 20 kidney transplant patients.
  • The management of deceased donors with potential infectious risks requires careful consideration.

Observation:

  • A 40-year-old male recipient developed a mycotic aneurysm of the renal artery graft.
  • The kidney graft was sourced from a deceased donor with an accidental digestive wound during organ retrieval.
  • Anuria presented 47 days post-transplantation, leading to the diagnosis.

Findings:

  • The patient presented with sudden anuria 47 days after receiving a kidney transplant.
  • A large mycotic aneurysm was discovered in the renal artery of the transplanted kidney graft.
  • The causative agent was identified as Candida species, a known cause of arteritis.

Implications:

  • This case underscores the risk of transmitting fungal infections, such as Candida, through organ transplantation.
  • Caution is advised when utilizing organs from donors with digestive breaches or other potential sources of infection.
  • Early recognition and management of mycotic aneurysms in transplant recipients are crucial for favorable outcomes.

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