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The development and validation of the Bronchiectasis Health Questionnaire.

Arietta Spinou1, Richard J Siegert2, Wei-Jie Guan3

  • 1Division of Asthma, Allergy and Lung Biology, Faculty of Life Sciences and Medicine, King's College London, London, UK.

The European Respiratory Journal
|May 13, 2017
PubMed
Summary
This summary is machine-generated.

A new Bronchiectasis Health Questionnaire (BHQ) was developed to assess patient health status. This brief, valid, and repeatable tool provides a single score for clinical use in managing bronchiectasis.

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Area of Science:

  • Pulmonary Medicine
  • Health Outcomes Research
  • Psychometrics

Background:

  • Bronchiectasis significantly impairs health-related quality of life.
  • A need exists for brief, disease-specific health status measures for bronchiectasis.
  • Existing measures lack simplicity and disease specificity.

Purpose of the Study:

  • To develop and validate the Bronchiectasis Health Questionnaire (BHQ).
  • To create a brief, disease-specific measure generating a single overall score.
  • To provide a patient-centered assessment tool for clinical practice.

Main Methods:

  • Item generation and reduction using Rasch analysis.
  • Validation and repeatability testing in a cohort of 206 patients.
  • Standardized translation into 11 languages.

Main Results:

  • The final BHQ comprises 10 items with good internal consistency (Cronbach's α=0.85).
  • BHQ demonstrated high convergent validity with St George's Respiratory Questionnaire (r=-0.82) and moderate correlation with lung function (r=-0.27).
  • BHQ scores correlated significantly with exacerbations, hospital admissions, and CT scan findings, and were repeatable (ICC=0.89).

Conclusions:

  • The Bronchiectasis Health Questionnaire (BHQ) is a brief, valid, and repeatable measure.
  • It effectively assesses health status from the patient's perspective in bronchiectasis.
  • The BHQ is suitable for clinical use to evaluate the impact of bronchiectasis.