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Use of 3D Robotic Ultrasound for In Vivo Analysis of Mouse Kidneys

Use of 3D Robotic Ultrasound for In Vivo Analysis of Mouse Kidneys

Published on: August 12, 2021

Percutaneous US-guided renal cryoablation using 3D modeling.

Leonid M Rapoport¹, Shmuel Cytron², Mikhail E Enikeev¹

¹Research Institute of Uronephrology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University, Moscow - Russia.

|May 13, 2017

Summary

Percutaneous ultrasound-guided cryoablation is effective for small renal tumors (T1a). This minimally invasive treatment shows promising safety and short-term results for selected kidney cancer patients.

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Area of Science:

Urology
Interventional Radiology
Oncology

Background:

Percutaneous ultrasound (US)-guided cryoablation is a novel technique for renal tumor treatment.
This study details the initial experience and evaluates the safety and short-term outcomes of this procedure.

Purpose of the Study:

To assess the safety and efficacy of percutaneous US-guided cryoablation for renal tumors.
To evaluate short-term results in patients with varying tumor characteristics.

Main Methods:

Twelve patients with renal tumors underwent US-guided cryoablation.
Tumor characteristics were assessed using the PADUA score; patients had tumors up to 3.0 cm (T1a) or 4.5 cm (T1b).
Renal Doppler US and contrast-enhanced CT were used for pre-procedure and 6-month follow-up assessments.

Main Results:

The average cryoablation time was 60 minutes, performed under spinal or local anesthesia.
After 6 months, 11 T1a tumors (up to 3.0 cm) showed size reduction and no blood supply.
One T1b tumor (4.5 cm) had partial response, necessitating subsequent laparoscopic resection; histology confirmed clear-cell carcinoma.

Conclusions:

Percutaneous US-guided cryoablation is a suitable primary treatment for T1a renal tumors.
Ideal candidates have tumors on the posterior/lateral surface, without sinus involvement, and a PADUA score less than 9.