Related Experiment Video
Updated: Jul 20, 2026
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Effect of pyrophosphate on protein adsorption to hydroxyapatite in vitro and on pellicle formation in vivo
Abstract:
This study showed that pyrophosphate (PP) desorbed an acidic protein (albumin) from hydroxyapatite (HA) more effectively than phosphate and that HA pretreated with PP took up markedly less protein than untreated HA. The protein which adsorbed to PP-treated HA was more loosely bound than that adsorbed to untreated HA. In vivo experiments showed that pellicle formed more slowly on PP-treated etched enamel than on untreated controls. The possible clinical implications of these findings are discussed.
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