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Metastasis02:30

Metastasis

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
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Metastatic Breast Cancer.

Olive Peart

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    Summary
    This summary is machine-generated.

    Metastatic breast cancer, which spreads beyond the breast, affects 12% of patients. While incurable, treatments can extend and improve the lives of those diagnosed with this advanced cancer.

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    Area of Science:

    • Oncology
    • Cancer Research

    Background:

    • Despite advances in breast cancer care, 12% of patients develop metastatic breast cancer.
    • Metastatic breast cancer has a poor prognosis, with a 5-year survival rate of 26%.

    Purpose of the Study:

    • To review breast cancer types and staging systems.
    • To discuss molecular subtypes, symptoms, and current treatments for metastatic breast cancer.

    Main Methods:

    • Literature review of breast cancer types.
    • Review of cancer staging systems.
    • Discussion of molecular subtypes, symptoms, and treatments.

    Main Results:

    • Metastatic breast cancer remains a significant challenge despite treatment advances.
    • Current treatments aim to improve and extend the lives of patients.

    Conclusions:

    • Understanding breast cancer types, staging, molecular subtypes, and symptoms is crucial.
    • Ongoing research and treatment advancements offer hope for managing metastatic breast cancer.