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Rhinophototherapy in chronic rhinosinusitis: a double blind randomized placebo-controlled trial
N Dulguerov1, N Guinand1, D Courvoisier2
1Department of OtoRhinoLaryngology, Head and Neck Surgery, Geneva University Hospital, Geneva, Switzerland.
Background:
This study evaluated the efficacy of rhinophototherapy in patients with chronic rhinosinusitis (CRS) without nasal polyps.
Method:
In this randomized double-blind, placebo-controlled trial, CRS patients (n=50) received either mixed visible and ultraviolet (UVA and UVB) light source application (mUV/VIS) or visible light alone that served as placebo. Both groups were treated for 3 weeks.
Results:
Results in the rhinophototherapy and placebo group were not significantly different and failed to reduce patient-reported outcomes measures (Rhinosinusits Disability Index, Visual Analogic Scale of symptom severity) and objective scores (rhinomanometry, olfactory thresholds, nasal Nitic Oxide concentrations), immediately and one month after treatment.
Conclusions:
The present data suggest that rhinophototherapy is not an efficient treatment for chronic rhinosinusitis without nasal polyps.
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