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Updated: Mar 2, 2026
An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
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Guillain Barré Syndrome in a Child With X-Linked Adrenoleukodystrophy
Ron Jacob1, Hanna Mandel2, Naim Shehadeh3
1Department of Pediatrics B, Ruth Rapport Children's Hospital, Rambam Health Care Campus, Technion Faculty of Medicine, Haifa, Israel.
Abstract:
X-Linked adrenoleukodystrophy is the most common peroxisomal disorder with different phenotypes among patients carrying the same ABCD1 mutation. There were previously reported associations of X-linked adrenoleukodystrophy with autoimmune disorders. The authors describe Guillain Barré syndrome in a child with X-linked adrenoleukodystrophy. The available evidence does not permit conclusion concerning etiological linkage between the 2 diseases, but it warrants further study.
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