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Seven-Digit Creatine Kinase in Acute Rhabdomyolysis in a Child
Nuha Basheer1,2, Sirin Mneimneh1,2, Mariam Rajab1,2
1Pediatric Department, Makassed General Hospital, Beirut, Lebanon.
Insights
This case report details a 3-year-old child with severe rhabdomyolysis, characterized by a 7-digit creatine kinase level due to viral myositis. The child recovered without needing renal dialysis, highlighting a rare but manageable outcome.
Area of Science:
- Pediatric Medicine
- Neurology
- Nephrology
Background:
- Rhabdomyolysis is a critical condition in children with diverse etiologies.
- Viral myositis and trauma are leading causes, potentially leading to acute kidney injury.
- Extremely elevated creatine kinase levels indicate severe muscle breakdown.
Purpose of the Study:
- To report an exceptionally high creatine kinase level in a pediatric rhabdomyolysis case.
- To highlight viral myositis as a cause of severe rhabdomyolysis in a child.
- To document the clinical course and management of a child with a 7-digit creatine kinase level.
Main Methods:
- Case report of a 3-year-old male child.
- Clinical presentation and laboratory findings, including peak plasma creatine kinase.
- Assessment of renal function and management decisions.
Main Results:
- The patient presented with acute rhabdomyolysis.
- Peak plasma creatine kinase reached a 7-digit level, exceeding previously reported cases.
- The child recovered without requiring renal dialysis.
Conclusions:
- Viral myositis can cause life-threatening rhabdomyolysis with extremely high creatine kinase levels in children.
- Severe rhabdomyolysis does not always necessitate renal dialysis.
- This case expands the understanding of pediatric rhabdomyolysis severity and outcomes.
Abstract:
Rhabdomyolysis is an acute life-threatening condition that can occur in childhood secondary to many causes. The authors report the case of a 3-year-old male child who presented with acute rhabdomyolysis. The peak plasma creatine kinase level was extremely high. The 2 main causes of rhabdomyolysis in childhood are viral myositis and trauma, which can sometimes lead to acute renal failure. The highest creatine kinase levels reported in the literature so far was a 6-digit level in 2014 case report. In this study, the authors report the case of a 7-digit creatine kinase level in a child secondary to viral myositis who did not require renal dialysis.
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