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Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
Insulin-mediated hypoglycaemia secondary to recurrent clear cell renal carcinoma
1G Gogna, Greenslopes Private Hospital, Newdegate Street, Greenslopes 4120, Brisbane, QLD, Australia. E-mail ggogna86@gmail.com.
Abstract:
Renal cell carcinoma has previously been associated with hypoglycaemia in the setting of non-islet cell tumours, caused by a paraneoplastic phenomenon relating to the production of insulin-like growth factor type II. We present a case of recurrent clear cell renal cell carcinoma, leading to an insulin-mediated paraneoplastic phenomenon causing severe recurrent hypoglycaemia. Hypoglycaemina was managed successfully using diazoxide therapy, in conjunction with pazopanib and radiotherapy to reduce tumour burden.
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