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Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
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ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

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Published on: January 16, 2019

HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens.

Christian Scheeder¹, Florian Heigwer¹, Michael Boutros¹

¹Division of Signaling and Functional Genomics, German Cancer Research Center (DKFZ) and Heidelberg University, 69120 Heidelberg, Germany.

Bioinformatics (Oxford, England)

|May 16, 2017

Summary

High-throughput screening (HTS) data analysis is challenging. HTSvis is a new web application that provides interactive visualization and quality control for HTS data, simplifying interpretation and integration of screening results.

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Last Updated: Mar 2, 2026

ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

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Published on: January 16, 2019

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

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Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

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Published on: January 2, 2011

Area of Science:

Genomics
Bioinformatics
Drug Discovery

Background:

High-throughput screening (HTS) generates large datasets.
Analyzing and visualizing HTS data is complex.
Existing tools lack user-friendly interpretation and integration capabilities.

Purpose of the Study:

To present HTSvis, a web application for interactive HTS data analysis.
To address the challenges in exploratory data analysis and integration of screening results.
To provide a user-friendly tool for visualization and quality control of HTS data.

Main Methods:

HTSvis is an open-source R package.
It allows interactive visualization of raw and analyzed HTS data.
Supports single to multi-channel measurements, including image-based screens.

Main Results:

HTSvis facilitates interactive visualization of HTS data.
Enables quality control and assessment of screening results.
Handles various assay types and data scales in a generic tabular format.

Conclusions:

HTSvis simplifies the analysis and interpretation of complex HTS datasets.
It offers a user-friendly solution for visualizing and integrating screening results.
The tool supports diverse HTS applications, improving data accessibility.