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[Intraindividual Keratoconus Progression].

Susanne Goebels1, Timo Eppig2, Berthold Seitz1

  • 1Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes, Homburg/Saar.

Klinische Monatsblatter Fur Augenheilkunde
|May 17, 2017
PubMed
Summary
This summary is machine-generated.

Keratoconus progression in one eye does not correlate with the fellow eye, indicating independent disease development. Age did not show a consistent relationship with keratoconus progression across all measured indices.

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Area of Science:

  • Ophthalmology
  • Corneal Diseases
  • Vision Science

Background:

  • Keratoconus is a progressive, typically bilateral corneal disease.
  • Understanding intraindividual progression is crucial for patient management.
  • Current research aims to clarify the independent progression of keratoconus between fellow eyes.

Purpose of the Study:

  • To evaluate the intraindividual progression of keratoconus.
  • To determine if keratoconus progression in one eye correlates with the fellow eye.
  • To assess the relationship between age and keratoconus progression using topographic indices.

Main Methods:

  • Retrospective analysis of topographic data from 48 non-operated keratoconus patients over two years.
  • Utilized seven topographical keratoconus indices derived from Scheimpflug tomography.
  • Compared initial findings and progression between fellow eyes.

Main Results:

  • Initial findings showed no significant correlation between fellow eyes (p > 0.05).
  • All indices demonstrated a negative correlation between baseline and progression (p < 0.05).
  • Progression correlated with age for Rmin and IHD; weak correlations found for ISV, IVA, and KI with intraindividual progression.

Conclusions:

  • Intraindividual asymmetry, characteristic of keratoconus, was confirmed.
  • Keratoconus progression in one eye appears independent of the fellow eye.
  • A consistent age-related progression of keratoconus was not demonstrated for all indices in this cohort.