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Sci-Fri AM: Imaging - 02: High resolution detectors for PET mammography.

S G Cuddy1, J A Rowlands1,2

  • 1Thunder Bay Regional Research Institute.

Medical Physics
|May 19, 2017
PubMed
Summary

A novel dual-ended readout block detector improves positron emission mammography (PEM) by measuring depth-of-interaction (DOI) to reduce parallax blurring. This enhances breast cancer screening accuracy, especially for dense breasts, without increasing detector count.

Keywords:
CancerImage detection systemsImage sensorsMammographyMedical imagingPhotodetectorsPhotoemission electron microscopyPhotonsPositronsScintillation detectors

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Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Biomedical Engineering

Background:

  • Positron emission mammography (PEM) offers high specificity for malignant breast lesions.
  • Improving sensitivity in dense breasts and reducing false positives are key goals for breast cancer screening.
  • High scintillation detector efficiency is crucial for signal-to-noise ratio and minimizing patient dose in PEM.

Purpose of the Study:

  • To develop a detector that increases photon detection efficiency by accepting wider incident angles.
  • To implement depth-of-interaction (DOI) measurement to minimize parallax blurring in PEM.
  • To design a detector minimizing photodetector count while enabling DOI measurement and crystal identification.

Main Methods:

  • A prototype dual-ended readout block (DERB) detector was constructed using silicon photomultiplier (SiPM) arrays and LYSO scintillation crystals.
  • The detector utilizes asymmetry of signals from dual photodetector arrays for DOI measurement.
  • Anger Logic with light sharing was employed to identify interacting crystal elements.

Main Results:

  • The DERB detector successfully identified interacting crystal elements.
  • DOI was measured with approximately 5mm resolution in 2mm x 2mm x 20mm crystals.
  • An average energy resolution of approximately 20% was achieved.

Conclusions:

  • The DERB detector effectively reduces parallax effects in PEM systems without requiring additional photodetectors.
  • This technology holds promise for enhancing PEM system performance.
  • Further research is needed to optimize performance with high-efficiency photodetectors.