Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of YouTube as an Information Platform for Ovarian Cancer: the Educational Quality and Reliability.

Yonsei medical journal·2026
Same author

Contribution of Myelin Damage to White Matter Changes in Osmotic Demyelination Syndrome.

Diagnostics (Basel, Switzerland)·2026
Same author

Leukemia-targeting NK cell nanoengagers effectively promote robust NK activation and potent anti-acute myeloid leukemia response.

Journal of nanobiotechnology·2026
Same author

Simulation and optimization of treatment schedule for multi-gantry heavy ion therapy.

Technical innovations & patient support in radiation oncology·2026
Same author

Acceptance testing of a 0.35 T MR-Linac: procedures, QA baseline, and system limitations.

Journal of applied clinical medical physics·2026
Same author

Deep learning-based dose prediction for prostate cancer with empty bladder protocol: a framework for efficient and personalized radiotherapy planning.

Frontiers in oncology·2026

Related Experiment Video

Updated: Mar 2, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

15.1K

SU-E-J-128: Liver Motion during CBCT-Guided SBRT.

Justin C Park1,2, Sung Ho Park1,2, Bongyong Song1,2

  • 1Center for Advanced Radiotherapy Technologies and Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, California 92093.

Medical Physics
|May 19, 2017
PubMed
Summary

Liver motion during SBRT varies significantly between and within fractions. Using fiducial markers closest to the liver tumor is recommended for accurate tracking and treatment.

Keywords:
Cone beam computed tomographyLiverRadiation therapy

More Related Videos

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.3K
Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
09:49

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

10.8K

Related Experiment Videos

Last Updated: Mar 2, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

15.1K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.3K
Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
09:49

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

10.8K

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Radiotherapy Technology

Background:

  • Accurate liver motion assessment is crucial for Stereotactic Body Radiation Therapy (SBRT).
  • Fiducial markers and Cone-Beam Computed Tomography (CBCT) are used to track organ motion during treatment.
  • Understanding intra- and inter-fractional motion variability is essential for optimizing treatment delivery.

Purpose of the Study:

  • To investigate the motion characteristics of the liver during SBRT.
  • To analyze liver motion using fiducial markers tracked via CBCT X-ray projections.
  • To evaluate motion patterns immediately prior to each treatment fraction.

Main Methods:

  • Tracking of fiducial markers using X-ray projections from CBCT scans.
  • Acquisition of CBCT scans immediately before each SBRT treatment.
  • Analysis of liver motion range and respiratory period in different directions (LR, AP, CC).

Main Results:

  • Liver motion range in LR, AP, and CC directions was quantified using 4DCT and CBCT data.
  • Breathing-induced anterior-posterior (AP) and cranio-caudal (CC) motions were found to be highly correlated.
  • A positive correlation (R²=0.69) was observed between the distance between markers and the difference in their motion magnitude.
  • Significant inter-fractional gating window variations were noted, with ranges up to 56.4%.

Conclusions:

  • Significant inter- and intra-fractional variations in liver motion during SBRT were observed.
  • Increased distance between fiducial markers correlated with increased differences in motion range.
  • Placement of fiducial markers in closest proximity to the liver tumor is recommended for improved accuracy.