WE-G-BRB-01: Per-Frame Analysis of MatriXX Data

One of the most widely used IMRT QA devices (MatriXX) is an array of ionization chambers which are periodically read during plan delivery. Although the ionization chambers are not expected to exhibit strong angular dependence, the measured dose distribution is often found to significantly differ from the planned dose distribution. We identify the origin of all factors that affect the measurement accuracy of the MatriXX and develop a per-frame post-processing strategy that reduces their impact on the passing rate of IMRT and VMAT plans.

We developed software that reads the dose frame sequence recorded by the MatriXX and applies a number of correction factors to each frame. Angular correction factors are computed as ratios of measured dose at the isocenter of the phantom and planned dose at the same location for all clinically used photon energies. For every clinical case, the recorded movie file is read and the dose for every frame is corrected according to the angle of the beam. In addition, the background evolution is tracked in the 'beam-off' frames which are subsequently subtracted from the 'beam-on' frames according to a predictive model. Machine output correction is also implemented, which significantly improves the absolute dose measurements. The IMRT effective plane of measurement of the MatriXX was identified and found not to coincide with the isocentric plane.

The clinical passing rates are significantly improved when the per-frame analysis software was introduced in our IMRT QA procedure. For a group of 800 patients with no corrections the average passing rate was 93.6%, while for the first 300 cases with per frame corrections the average passing rate was 97.3%.

We identify all factors that impact the measurement accuracy of the MatriXX (angular effects, background evolution, machine output, plane of measurement) and propose a strategy for their elimination.