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WE-G-213CD-04: A Triggering System to Guide 4DMRI Image Acquisition.

Y Hu^1,1,2,1,1, S Caruthers^1,1,2,1,1, D Low^1,1,2,1,1

¹Washington University School of Medicine, Saint Louis, MO.

Medical Physics

|May 19, 2017

Summary

A new system prospectively triggers Magnetic Resonance Imaging (MRI) acquisition for four-dimensional MRI (4DMRI) to track abdominal tumor motion. This T2-weighted 4DMRI offers improved tumor-tissue contrast for radiotherapy planning.

Keywords:

Cancer Digital image processing Image scanners Magnetic resonance imaging Medical imaging Medical treatment planning Physiology Pneumodynamics Radiation therapy Spin echoes

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Area of Science:

Medical Imaging
Radiotherapy
Biomedical Engineering

Background:

Accurate tracking of abdominal tumor motion during radiotherapy is crucial for treatment planning.
Four-dimensional Magnetic Resonance Imaging (4DMRI) is a promising technique for motion tracking.
Previous 4DMRI techniques often utilized T1 or T2/T1 weighting, limiting tumor-tissue contrast.

Purpose of the Study:

To develop a practical triggering system for prospective image acquisition in 4DMRI.
To guide 4DMRI acquisition based on pre-selected respiratory amplitudes for abdominal tumor motion tracking.
To enable T2-weighted 4DMRI for improved tumor visualization in radiotherapy planning.

Main Methods:

A novel triggering system was developed, comprising preparation and acquisition stages.
Respiration is monitored using an external belt, dividing the respiratory cycle into N states.
Each respiratory state triggers the acquisition of a single slice, forming a complete 4DMRI dataset.

Main Results:

The system successfully triggered image acquisition at expected physiological points.
Four T2-weighted images demonstrated the tracking of liver motion across four respiratory states.
The proof-of-principle was validated on a healthy subject using a clinical 1.5T MRI scanner.

Conclusions:

The developed system prospectively guides 4DMRI acquisition for T2-weighted imaging.
This T2-weighted 4DMRI provides superior tumor-tissue contrast compared to prior methods.
This represents the first report of pure T2-weighted 4DMRI for tracking respiration-induced abdominal motion.