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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Related Experiment Video

Updated: Mar 2, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
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Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

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[Asthma and obesity].

R Trokart1, S Demarche2, F Schleich3

  • 1Faculté de Médecine, Université de Liège, Belgique.

Revue Medicale De Liege
|May 19, 2017
PubMed
Summary
This summary is machine-generated.

Obesity significantly worsens asthma control and reduces treatment effectiveness, particularly for inhaled corticosteroids. Weight loss is crucial for improving asthma management in obese patients.

Keywords:
InflammationObesityVentilatory mechanicsWeight lossAsthma

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Area of Science:

  • Pulmonology
  • Metabolic Diseases

Background:

  • Asthma and obesity are prevalent chronic conditions.
  • Obesity affects 20% of asthma patients, rising to 25% in severe cases within the Belgian Severe Asthma national Registry.
  • Obesity impairs thoracic mechanics, increasing asthma symptom burden and reducing control.

Purpose of the Study:

  • To investigate the impact of obesity on asthma control and treatment response.
  • To highlight the significance of weight management in obese asthma patients.

Main Methods:

  • Analysis of patient data from an asthma clinic and the Belgian Severe Asthma national Registry.
  • Assessment of asthma control and response to inhaled corticosteroids in obese versus non-obese individuals.

Main Results:

  • Obese asthmatics exhibit poorer asthma control and a diminished response to inhaled corticosteroids.
  • Weight loss interventions are associated with significant improvements in asthma control.

Conclusions:

  • Obesity is a critical factor negatively influencing asthma management.
  • Weight loss should be a primary therapeutic goal for obese patients with asthma to enhance disease control and treatment efficacy.