Measuring and using free drug concentrations: has there been 'real' progress?

Influence of Sampling Site and Fluid Flow on the Accuracy of Total Body Clearance Calculation.

Journal of pharmaceutical sciences·2020

In vivo monitoring of rat brain endocannabinoids using solid-phase microextraction.

Bioanalysis·2019

Transdermal sampling of vitamin D3 and 25-hydroxyvitamin D3.

Bioanalysis·2018

Normalized vitamin D metabolite concentrations are better correlated to pharmacological effects than measured concentrations.

Future science OA·2016

Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia.

Journal of leukocyte biology·2016

Evaluation of in vivo solid phase microextraction for minimally invasive analysis of nonvolatile phytochemicals in Amazonian plants.

Analytica chimica acta·2016

Reference values for urinary 2-phenyl-2-propanol as a biomarker of cumene exposure in a non-occupationally exposed population determined by GC-MS.

Bioanalysis·2026

A UHPLC-MS/MS method for the simultaneous quantification of BTK inhibitors and their active metabolite in human plasma and cerebrospinal fluid.

Bioanalysis·2026

Drawing a line in the sand: impact of analytical choices on anti-drug antibody cut-points and testing outcomes.

Bioanalysis·2026

Quantification of HSK21542 in rat plasma and tissues by LC-MS/MS: an application to pharmacokinetics and tissue distribution study.

Bioanalysis·2026

Limited agreement of cytokines and CRP through patient-centric microsampling compared to venipuncture in healthy adults.

Bioanalysis·2026

A simple, sensitive microsample LC-MS assay for quercetin and isorhamnetin in mouse and human plasma: application to EMIQ treatment in myotonic dystrophy type 1.

Bioanalysis·2026

Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series.

Clinical practice and cases in emergency medicine·2026

Comparative bioavailability of three benznidazole formulations in healthy individuals: a randomised study.

Memorias do Instituto Oswaldo Cruz·2026

A Regulatory-Ready Bayesian Evidence Framework across Clinical Development and Pharmacovigilance: Practical Expectations from FDA, EMA, and ICH Guidance.

Therapeutic innovation & regulatory science·2026

Patient Access to Buprenorphine at Community Pharmacies: A Scoping Review of Audit Studies.

Journal of addiction medicine·2026

Immunomodulatory Activity of Phenylephrine on LPS Stimulated Macrophages.

Immunopharmacology and immunotoxicology·2026

Postoperative Mortality Following Extended-Release Buprenorphine, Carprofen, and Bupivacaine Administration in Male ACI Rats (Rattus norvegicus).

Journal of the American Association for Laboratory Animal Science : JAALAS·2026

Related Experiment Videos

Measuring and using free drug concentrations: has there been 'real' progress?

Related Concept Videos

Influence of Sampling Site and Fluid Flow on the Accuracy of Total Body Clearance Calculation.

<i>In vivo</i> monitoring of rat brain endocannabinoids using solid-phase microextraction.

Transdermal sampling of vitamin D<sub>3</sub> and 25-hydroxyvitamin D<sub>3</sub>.

Normalized vitamin D metabolite concentrations are better correlated to pharmacological effects than measured concentrations.

Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia.

Evaluation of in vivo solid phase microextraction for minimally invasive analysis of nonvolatile phytochemicals in Amazonian plants.

Reference values for urinary 2-phenyl-2-propanol as a biomarker of cumene exposure in a non-occupationally exposed population determined by GC-MS.

A UHPLC-MS/MS method for the simultaneous quantification of BTK inhibitors and their active metabolite in human plasma and cerebrospinal fluid.

Drawing a line in the sand: impact of analytical choices on anti-drug antibody cut-points and testing outcomes.

Quantification of HSK21542 in rat plasma and tissues by LC-MS/MS: an application to pharmacokinetics and tissue distribution study.

Limited agreement of cytokines and CRP through patient-centric microsampling compared to venipuncture in healthy adults.

A simple, sensitive microsample LC-MS assay for quercetin and isorhamnetin in mouse and human plasma: application to EMIQ treatment in myotonic dystrophy type 1.

Intravenous Low-dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series.

Comparative bioavailability of three benznidazole formulations in healthy individuals: a randomised study.

A Regulatory-Ready Bayesian Evidence Framework across Clinical Development and Pharmacovigilance: Practical Expectations from FDA, EMA, and ICH Guidance.

Patient Access to Buprenorphine at Community Pharmacies: A Scoping Review of Audit Studies.

Immunomodulatory Activity of Phenylephrine on LPS Stimulated Macrophages.

Postoperative Mortality Following Extended-Release Buprenorphine, Carprofen, and Bupivacaine Administration in Male ACI Rats (Rattus norvegicus).

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Measuring and using free drug concentrations: has there been 'real' progress?

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