[THE ASSOCIATION BETWEEN OBESITY AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)]
Shahar Geva1, Moria Yaakoby1, Or Kalchiem-Dekel1,2
1Department of Medicine B, Ben-Gurion University, Soroka University Medical Center, Beer-Sheva, Israel.
Harefuah
|May 23, 2017
Summary
Obesity and male gender may protect against hospitalizations for chronic obstructive pulmonary disease (COPD) exacerbations. Obese COPD patients also show better lung function, though survival is unaffected.
Area of Science:
- Pulmonology
- Obesity Medicine
Background:
- Chronic obstructive pulmonary disease (COPD) presents with respiratory and systemic effects.
- Obesity (BMI > 30 kg/m²) prevalence has doubled, with its relationship to COPD being unclear.
- Obesity is linked to increased survival in COPD patients, contrasting general population outcomes.
Purpose of the Study:
- To compare obese and non-obese patients with COPD.
- To assess differences in COPD exacerbation-related hospital admissions between groups.
Main Methods:
- Retrospective cohort study of 323 COPD patients (2003-2010).
- Data collected included demographics, medical history, BMI, lung function, hospital admissions, and mortality.
- Patients were categorized as obese (95) or non-obese (228).
Main Results:
- Non-obese COPD patients were 1.6 times more likely to be hospitalized for exacerbations.
- Women were 1.8 times more likely to be hospitalized.
- Obese COPD patients exhibited higher FEV1 and FEV1/FVC ratios.
- No significant difference in mortality was observed between obese and non-obese groups.
Conclusions:
- Obesity and male gender appear protective against COPD exacerbation hospitalizations.
- Obese COPD patients demonstrate superior lung function parameters.
- Obesity does not impact COPD patient survival.
- Further research is needed to establish nutritional guidelines and target weights for COPD management.
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