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[Liver morphology and clinical aspects of a case of cholesterol ester storage disease]
J Justus1, J Schulze, C Kemmer
1Institut für Pathologie Georg Schmorl, Medizinischen Akademie Carl Gustav Carus, Dresden.
Deutsche Zeitschrift Fur Verdauungs- Und Stoffwechselkrankheiten
|January 1, 1988
Abstract:
Liver specimen morphology and clinical course of a case of cholesterol ester storage disease are presented. In a 16-year-old boy on the first biopsy a massive storage of neutral fats was found light microscopically and of cholesterol ester micropolariscopically. Advanced portal field fibrosis and severe reactive hepatitis indicate the danger of progression up to metaplasia. Typical membrane-surrounded lipid inclusions were found electron microscopically in hepatic cells, stellate cells and also in bile duct epithelium.