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Subsyndromal Delirium.

Sue E Levkoff1, Benjamin Liptzin1, Paul D Cleary1

  • 1Harvard Medical School, Boston, MA.

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
|May 23, 2017
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Summary
This summary is machine-generated.

Subsyndromal delirium is part of a spectrum of neurobehavioral impairment, not a distinct condition. Early identification and treatment of subsyndromal delirium are crucial for reducing patient morbidity.

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Area of Science:

  • Geriatrics
  • Neuroscience
  • Clinical Medicine

Background:

  • Delirium is a common acute neuropsychiatric disorder in hospitalized patients.
  • Subsyndromal delirium, a milder form, requires further investigation to understand its clinical significance.
  • Distinguishing subsyndromal delirium from full delirium is important for patient management.

Purpose of the Study:

  • To investigate whether subsyndromal delirium represents a distinct clinical entity or a spectrum of cognitive and behavioral abnormalities.
  • To analyze risk factors associated with subsyndromal delirium and full delirium.
  • To determine the clinical implications of subsyndromal delirium.

Main Methods:

  • Prospective, longitudinal study of 325 acute care hospital patients.
  • Classification of patients into three groups: full delirium, subsyndromal delirium, and no delirium symptoms.
  • 3- and 6-month follow-ups to assess outcomes.

Main Results:

  • No significant differences in risk factors were found between patients with subsyndromal delirium and those with full delirium.
  • The number of independent risk factors significantly predicted delirium development.
  • Patients with subsyndromal delirium demonstrated a continuum of impairment between those with full delirium and those without symptoms.

Conclusions:

  • Delirium appears to represent a spectrum of neurobehavioral impairment.
  • Subsyndromal delirium is associated with significant patient morbidity.
  • Clinicians should focus on reducing and treating subsyndromal delirium to mitigate adverse outcomes.