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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: Mar 2, 2026

Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

Published on: February 2, 2015

Imaging Glaucoma.

Donald C Hood¹

¹Departments of Psychology and Ophthalmology, Columbia University, New York, NY 10027;

Annual Review of Vision Science

|May 24, 2017

Summary

This summary is machine-generated.

Optical coherence tomography (OCT) advances glaucoma diagnosis by measuring retinal nerve fiber and RGC layer thickness. This technology reveals greater macular damage than previously understood, improving our understanding of glaucoma progression.

Keywords:

adaptive optics glaucoma optical coherence tomography visual fields

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Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Area of Science:

Ophthalmology
Neuroscience
Medical Imaging

Background:

Glaucoma is a leading cause of irreversible blindness.
It damages retinal ganglion cell (RGC) axons and RGC bodies.
Current diagnostic methods have limitations in quantifying structural damage.

Purpose of the Study:

To describe Optical Coherence Tomography (OCT) techniques for glaucoma research.
To investigate the extent of RGC and retinal nerve fiber (RNF) layer thinning in glaucoma.
To explore the relationship between structural damage and behavioral data.

Main Methods:

Noninvasive measurement of RNF and RGC layer thickness using OCT.
Application of OCT for studying glaucomatous damage patterns.
Utilizing an anatomical model to explain observed damage.

Main Results:

OCT enables precise measurement of RNF and RGC layer thinning.
Glaucoma causes significant damage to the macula, exceeding prior estimations.
OCT data correlates RGC/RNF loss with behavioral deficits.

Conclusions:

OCT is a transformative tool for glaucoma diagnosis and research.
Understanding macular involvement in glaucoma is crucial.
OCT enhances the correlation of structural changes with functional vision loss.