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Author Spotlight: Learning Systematic Bronchoscopy in a Simulation-Base Setting
Published on: June 23, 2023
Flexible Bronchoscopy in Non-resolving Pneumonia
Javeed Iqbal Bhat1, Wasim Ahmad Wani2, Qazi Iqbal Ahmad2
1Department of Pediatrics, SKIMS, Srinagar, Jammu and Kashmir, 190011, India. drjaveediqbal@gmail.com.
Insights
Flexible bronchoscopy and bronchoalveolar lavage (BAL) are safe and effective for diagnosing non-resolving pneumonia in children. Early use aids in identifying infections, foreign bodies, and airway abnormalities.
Area of Science:
- Pediatric Pulmonology
- Diagnostic Procedures
- Infectious Diseases
Background:
- Non-resolving pneumonia presents a diagnostic challenge in pediatric patients.
- Identifying the underlying etiology is crucial for effective management.
Purpose of the Study:
- To evaluate the diagnostic utility of flexible bronchoscopy and bronchoalveolar lavage (BAL) in children with non-resolving pneumonia.
- To determine the spectrum of abnormalities and causative organisms identified by these procedures.
Main Methods:
- A cross-sectional study included 52 children (1 month to 14 years) with non-resolving pneumonia.
- Flexible bronchoscopy was performed, with bronchoalveolar lavage (BAL) collected for microbiological and cytological analysis.
- BAL analysis included Gram staining, culture, GeneXpert, and lipid-laden macrophage examination.
Main Results:
- Flexible bronchoscopy yielded a definitive diagnosis in 30.7% of cases.
- Bronchoalveolar lavage (BAL) cultures were positive for organisms in 52.3% of children.
- Morphological abnormalities, including foreign bodies, were identified in several patients.
Conclusions:
- Flexible bronchoscopy and BAL are valuable tools for diagnosing non-resolving pneumonia in children.
- These procedures help identify infectious and non-infectious causes, such as tracheobronchomalacia and foreign body aspiration.
- Early application of bronchoscopy and BAL analysis can significantly guide diagnosis and treatment.
Objective:
To study the utility of diagnostic flexible bronchoscopy and bronchoalveolar lavage (BAL) in children with non-resolving pneumonia.
Methods:
This was a cross-sectional study conducted in a tertiary care hospital from July 2015 through June 2016. Fifty-two consecutive children of both genders from 1 mo to 14 y of age with a diagnosis of non-resolving pneumonia were included. Flexible bronchoscopy was done in all patients with or without bronchoalveolar lavage (BAL). BAL was sent for gram staining, culture, gene expert™ and lipid laden macrophages examination. Main outcome measures were to find any morphological abnormality in the tracheobronchial tree and organism profile of a positive BAL culture.
Results:
During the period of 12 mo, 52 consecutive patients of non-resolving pneumonia were enrolled. Median (IQR) age of the study population was 12 (68.8) mo. Mean ± SD duration of illness was 22.7 ± 5.6 d. Flexible bronchoscopy was found to be very safe and effective tool that directly led to definitive diagnosis in 30.7% of cases. It was positive for different organisms in 22 (52.3%) children. Neglected foreign body was seen in five patients.
Conclusions:
Non-resolving pneumonia is often an area of clinical dilemma. Bacterial infections are the commonest etiology. Non-infectious causes like tracheobronchomalacia and foreign body aspiration are other important etiologies to be looked for. Early bronchoscopy and bronchoalveolar lavage analysis can play a crucial role in the evaluation of these patients and may provide an important clue or strongly support the specific diagnosis.
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