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A case of false positive Troponin I in a patient affected by cryoglobulinemic vasculitis
M Bellan1, M Pirisi, G Bellomo
1Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara. bellanmattia@yahoo.it.
Abstract:
Troponin I (TnI) false positive results have been reported in patients affected by immune disorders. We report the case of a 74-year-old woman affected by cryoglobulinemic vasculitis, admitted to the Emergency Room because of a lipotimic episode. A marked elevation of TnI plasma concentration was confirmed in multiple determinations, despite the absence of symptoms or electrocardiogram findings suggesting myocardial infarction. TnI plasma concentration was reported normal after re-testing with a different commercial kit. A false TnI positivity should be considered in patients with immune disorders, especially if seropositive for rheumatoid factor, when the clinical context does not suggest myocardial infarction.
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