Clinical and electrocardiographic characteristics of infarctional ventricular ectopic beats: An observational study
Yuechun Li1, Shi Zhe-Wei, Zheng Cheng
1Department of Cardiology, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Insights
Infarctional ventricular ectopic beats (IVEBs) are common in acute myocardial infarction (AMI). These IVEBs provide valuable early diagnostic clues for identifying the location and extent of AMI.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Acute myocardial infarction (AMI) diagnosis relies on clinical symptoms, ECG, and cardiac biomarkers.
- Infarctional ventricular ectopic beats (IVEBs) are a specific type of arrhythmia observed during AMI.
- Understanding IVEB characteristics can potentially improve early AMI detection and localization.
Purpose of the Study:
- To investigate the clinical and electrocardiographic features of infarctional ventricular ectopic beats (IVEBs).
- To determine the association of IVEBs with specific AMI characteristics and outcomes.
Main Methods:
- Retrospective analysis of 38 AMI patients with IVEB and 109 AMI patients without IVEB.
- Comparison of QRS complex, ST segment, and T wave morphology in IVEB versus sinus rhythm.
- Statistical analysis including single-factor and multivariable logistic regression.
Main Results:
- IVEBs commonly present with right bundle branch block morphology and are associated with Q wave AMI.
- IVEBs correlate significantly with early AMI (<6 hours), larger infarct size, and thrombolytic reperfusion.
- Electrocardiographic changes in IVEB (wider Q wave, higher ST elevation) precede those in sinus rhythm and elevated myocardial enzymes.
Conclusions:
- Infarctional ventricular ectopic beats are not rare in AMI patients.
- IVEBs are valuable indicators for the early diagnosis and localization of acute myocardial infarction.
- The specific ECG patterns of IVEB can aid in rapid AMI assessment.
Abstract:
The purpose of this study was to explore the clinical and electrocardiographic characteristics of infarctional ventricular ectopic beats (IVEBs).Thirty-eight acute myocardial infarction (AMI) patients with IVEB and 109 AMI patients without IVEB were analyzed. The morphological changes of QRS complex, ST segment, and T wave were compared to IVEB with sinus rhythm from the same period and fully evolved phase.An IVEB QRS complex often revealed the right bundle branch block morphology, in addition to Q wave AMI; no-Q wave AMI also had IVEB. Single-factor analysis found that IVEB often appeared in early AMI (<6 hours), and they were more frequent in inferoposterior with/without right ventricular involvement, large area AMI and thrombolytic reperfusion than in anterior or anteroseptal myocardial infarction, small area AMI, and unthrombolytic nonreperfusion. Multifactors no conditional logistic regression analysis revealed a positive correlation between IVEB and early AMI, AMI size, Killip heart function degree, inferoposterior with/without right ventricular involvement, and thrombolytic reperfusion. The Q wave of IVEB was wider, and the ST segment elevation was higher than those of the same period in sinus rhythms. The infarctional morphological changes of IVEB could be found before the same period in sinus rhythm and elevated myocardial enzymes.IVEBs were not rare. They were useful for early diagnosis and location of AMI.
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