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Microbial Keratitis at an Urban Public Hospital: A 10-Year Update
David T Truong1, Minh-Thuy Bui1, Pauras Memon1
1Department of Ophthalmology, UT Southwestern Medical Center, USA.
Journal of Clinical & Experimental Ophthalmology
|May 26, 2017
Summary
Microbial keratitis remains a challenge, with contact lens wear increasing Pseudomonal infections. Despite treatment shifts, visual outcomes improved, and complication rates decreased in this urban hospital study.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Epidemiology
Background:
- Microbial keratitis is a significant cause of vision loss.
- Understanding trends in microbial keratitis is crucial for effective management.
- Previous studies provide a baseline for comparison.
Purpose of the Study:
- To review the epidemiology, risk factors, and treatment of microbial keratitis.
- To compare current findings with data from a decade prior.
- To identify changes in causative organisms and treatment outcomes.
Main Methods:
- Retrospective chart review of 318 microbial keratitis cases (2009-2014).
- Comparison with a previous study cohort (2000-2004).
- Analysis of best-corrected visual acuity (BCVA), risk factors, microbiology, and treatment.
Main Results:
- Contact lens wear, trauma, and ocular surface disease were primary risk factors.
- Gram-positive and gram-negative organisms were most common; no resistance to aminoglycosides/vancomycin.
- Improved BCVA and reduced complication rates compared to the earlier study.
- Increased contact lens-related Pseudomonas infections noted.
Conclusions:
- Microbial keratitis presents ongoing challenges in urban public hospitals.
- Epidemiology has shifted towards contact lens-related Pseudomonas infections.
- Visual outcomes have improved despite changes in diagnostic and treatment approaches.
