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Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
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Asthma-IV: Diagnostic and Management01:30

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Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
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Murine Model of Allergen Induced Asthma
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Allergen Avoidance in Allergic Asthma.

Francesca Cipriani1, Elisabetta Calamelli1,2, Giampaolo Ricci1

  • 1Pediatric Unit, S. Orsola-Malpighi Hospital, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Frontiers in Pediatrics
|May 26, 2017
PubMed
Summary
This summary is machine-generated.

Preventing allergic asthma in children involves controlling indoor allergen exposure. While evidence is debated, allergen avoidance remains a recommended strategy for managing respiratory symptoms.

Keywords:
allergenasthmaavoidancechildhoodexposuremitemoldpets

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Area of Science:

  • Pediatric Allergy and Immunology
  • Environmental Health
  • Respiratory Medicine

Background:

  • Allergic asthma is a prevalent chronic respiratory condition in children, significantly impacting public health.
  • Effective preventive strategies are crucial for managing symptoms and improving long-term outcomes in pediatric asthma patients.
  • Indoor allergen exposure is a primary trigger for allergic asthma, necessitating targeted control interventions.

Purpose of the Study:

  • To review recent literature on the efficacy of specific interventions for controlling major indoor allergens in allergic asthma.
  • To evaluate the evidence supporting various allergen control methods for sensitized individuals with respiratory allergies.

Main Methods:

  • Systematic literature review of studies investigating indoor allergen control interventions for allergic asthma.
  • Analysis of evidence regarding the effectiveness of allergen avoidance and reduction strategies.

Main Results:

  • A wide range of interventions exist to reduce indoor allergen exposure for sensitized patients.
  • Current evidence supporting the efficacy of these specific allergen control approaches is limited and often controversial.
  • Despite weak evidence, allergen exposure control is generally recommended as part of a comprehensive asthma management plan.

Conclusions:

  • Allergen avoidance is a cornerstone of managing allergic asthma, particularly in pediatric populations.
  • Further research is needed to establish definitive evidence for the effectiveness of specific indoor allergen control measures.
  • A holistic approach, including allergen control, is vital for reducing the severity of allergic respiratory symptoms.