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Updated: Mar 1, 2026

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
Published on: January 20, 2022
Online measurement of photoisomerisation efficiency in solution using ion mobility mass spectrometry
James N Bull1, Eduardo Carrascosa, Michael S Scholz
1School of Chemistry, University of Melbourne, Melbourne, VIC 3010, Australia. evanjb@unimelb.edu.au.
Abstract:
The photoisomerisation of charged molecules in solution is probed directly using ion mobility mass spectrometry with electrospray ionisation. The technique is demonstrated using a prototype azoheteroarene cation in methanol. By scanning the wavelength of the excitation light while monitoring the photoisomer intensity a photoisomerisation action spectrum is generated, which, when compared with a conventional absorption spectrum, allows the relative photoisomerisation quantum yield to be determined across a range of wavelengths.
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