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Author Spotlight: Studying Host-Microbe Interactions in Wound Biofilm Formation
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Atypical Wound Pathogens.

Philip S Barie1

  • 1Departments of Surgery and Medicine, Weill Cornell Medicine , New York, New York.

Surgical Infections
|May 26, 2017
PubMed
Summary
This summary is machine-generated.

Atypical wound pathogens, often difficult to isolate, include diverse bacteria like Mycoplasma and rapidly growing mycobacteria. These opportunistic agents commonly cause wound infections, presenting diagnostic challenges.

Keywords:
gram-negative bacilligram-positive coccinon-tuberculous mycobacteriasurgical site infection

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Area of Science:

  • Microbiology
  • Infectious Diseases

Background:

  • Atypical wound pathogens are defined by their uncommon occurrence in human soft tissue infections or laboratory isolation difficulties.
  • These pathogens encompass a broad range of microorganisms, including fastidious bacteria.

Purpose of the Study:

  • To review and characterize atypical wound pathogens.
  • To identify common atypical pathogens responsible for human wound infections.

Main Methods:

  • A comprehensive review of English-language literature was conducted.

Main Results:

  • Atypical pathogens include diverse aerobic and anaerobic gram-positive and gram-negative bacilli.
  • This group also comprises non-tuberculous mycobacteria and cell-wall-deficient bacteria (Mycoplasmataceae).
  • Many of these opportunistic pathogens exhibit varied virulence.

Conclusions:

  • Mycoplasma/Ureaplasma and rapidly growing non-tuberculous mycobacteria (Runyon Type IV, e.g., M. chelonae) are the most frequently reported atypical pathogens in clinical wound infections.
  • These organisms can act as co-infecting agents.