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Cardiovascular magnetic resonance imaging: clinical implications in the evaluation of connective tissue diseases

Sophie Mavrogeni1, George Markousis-Mavrogenis1, Loukia Koutsogeorgopoulou2

  • 1Onassis Cardiac Surgery Center, Athens, Greece.

Journal of Inflammation Research
|May 27, 2017
PubMed

Insights

Cardiovascular magnetic resonance imaging (CMR) offers a noninvasive method for diagnosing heart conditions in connective tissue diseases (CTDs). Despite its benefits in early detection and monitoring, barriers like cost and expert availability hinder widespread clinical use.

Area of Science:

  • Cardiology
  • Radiology
  • Rheumatology

Background:

  • Connective tissue diseases (CTDs) frequently involve serious cardiovascular complications, including myopericarditis, vascular disease, and heart failure.
  • These complications contribute significantly to morbidity and mortality in CTD patients.
  • Early and accurate cardiovascular diagnosis, risk stratification, and treatment monitoring are crucial for managing CTDs.

Purpose of the Study:

  • To evaluate the utility of cardiovascular magnetic resonance imaging (CMR) as a diagnostic tool for cardiovascular involvement in CTDs.
  • To highlight CMR's capabilities in early detection, disease assessment, and treatment monitoring.
  • To discuss the challenges limiting the broader clinical adoption of CMR in this context.

Main Methods:

  • Cardiovascular magnetic resonance imaging (CMR) was employed as a noninvasive, nonradiating diagnostic technique.
  • The study reviewed CMR's application in evaluating various cardiovascular conditions associated with CTDs.
  • Tissue characterization and high spatial resolution capabilities of CMR were considered.

Main Results:

  • CMR has demonstrated success in evaluating diverse cardiovascular conditions, including cardiomyopathies, valvular diseases, and myocardial perfusion.
  • It can detect early, silent cardiovascular lesions and assess disease activity in CTDs.
  • CMR reliably evaluates the impact of cardiac and rheumatic medications on the cardiovascular system.

Conclusions:

  • Cardiovascular magnetic resonance imaging is a versatile, noninvasive tool for diagnosing and managing cardiovascular complications in CTDs.
  • Its ability to provide detailed tissue characterization aids in early detection and risk stratification.
  • Wider adoption is currently limited by factors such as cost, availability, and the need for multidisciplinary expertise.

Keywords:
cardiovascular magnetic resonance imagingconnective tissue diseases

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