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Updated: Mar 1, 2026

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
Flavonoids: promising natural compounds against viral infections
Hovakim Zakaryan1, Erik Arabyan2, Adrian Oo3
1Group of Antiviral Defense Mechanisms, Institute of Molecular Biology of NAS RA, Hasratyan 7, 0014, Yerevan, Armenia. h_zakaryan@mb.sci.am.
Abstract:
Flavonoids are widely distributed as secondary metabolites produced by plants and play important roles in plant physiology, having a variety of potential biological benefits such as antioxidant, anti-inflammatory, anticancer, antibacterial, antifungal and antiviral activity. Different flavonoids have been investigated for their potential antiviral activities and several of them exhibited significant antiviral properties in in vitro and even in vivo studies. This review summarizes the evidence for antiviral activity of different flavonoids, highlighting, where investigated, the cellular and molecular mechanisms of action on viruses. We also present future perspectives on therapeutic applications of flavonoids against viral infections.
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