Related Experiment Video
Updated: Mar 1, 2026

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
Published on: February 10, 2020
Esophageal replacement
Shaun M Kunisaki1, Arnold G Coran1
1Section of Pediatric Surgery, Department of Surgery, C.S. Mott Children׳s Hospital, University of Michigan Medical School, 1540 E. Hospital Dr, SPC 4211, Ann Arbor, Michigan.
Abstract:
This article focuses on esophageal replacement as a surgical option for pediatric patients with end-stage esophageal disease. While it is obvious that the patient׳s own esophagus is the best esophagus, persisting with attempts to retain a native esophagus with no function and at all costs are futile and usually detrimental to the overall well-being of the child. In such cases, the esophagus should be abandoned, and the appropriate esophageal replacement is chosen for definitive reconstruction. We review the various types of conduits used for esophageal replacement and discuss the unique advantages and disadvantages that are relevant for clinical decision-making.
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