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Updated: Mar 1, 2026

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Published on: February 19, 2021
Multiple-coil k-space interpolation enhances resolution in single-shot spatiotemporal MRI
Gilad Liberman1, Eddy Solomon1, Michael Lustig2
1Department of Chemical Physics, Weizmann Institute of Science, Rehovot, Israel.
Spatio-temporal encoding (SPEN) with multiple receivers enhances MRI resolution without artifacts. This Super-resolved SPEN with SENSE (SUSPENSE) method achieves single-shot submillimeter imaging, enabling faster and clearer scans.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Image Reconstruction
- Signal Processing
Background:
- Spatio-temporal encoding (SPEN) offers artifact-free, single-scan MRI.
- Existing SPEN methods can be limited by folding, chemical shift, and susceptibility artifacts.
- Resolution enhancement in SPEN is crucial for advanced diagnostic imaging.
Purpose of the Study:
- To introduce a novel method for enhancing SPEN resolution using multiple receivers.
- To demonstrate artifact reduction and improved image quality in SPEN.
- To achieve single-shot submillimeter in-plane resolutions without compromising scan speed.
Main Methods:
- Developed a Super-resolved SPEN with SENSE (SUSPENSE) technique.
- Utilized k-space data interpolation enabled by multiple receiver coils.
- Implemented procedures akin to simultaneous acquisition of spatial harmonics and sensitivity encoding, but without fold-over constraints.
Main Results:
- Validated theoretical expectations through phantom and human volunteer experiments on a 3T scanner.
- Achieved significant resolution enhancement without increasing sequence complexity.
- Demonstrated 48-slice full-brain coverage at submillimeter resolution in 3 seconds, free from distortions, using multibanding and stimulated echo.
Conclusions:
- SUSPENSE successfully achieves the goals of multishot SPEN interleaving.
- Enables single-shot submillimeter in-plane resolutions in scanners with multiple sensors.
- Offers a robust and efficient method for high-resolution, artifact-free MRI.
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