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Related Concept Videos

Thermoregulation01:26

Thermoregulation

2.6K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
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Body Temperature01:25

Body Temperature

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The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
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Body Temperature01:07

Body Temperature

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Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
1.6K
Thermosensation01:43

Thermosensation

34.1K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
34.1K
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

4.3K
Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
4.3K
Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

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As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
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Related Experiment Video

Updated: Mar 1, 2026

Slice It Hot: Acute Adult Brain Slicing in Physiological Temperature
08:46

Slice It Hot: Acute Adult Brain Slicing in Physiological Temperature

Published on: October 30, 2014

28.4K

How a brain keeps its cool.

Swathi Yadlapalli1, Orie T Shafer1

  • 1Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, United States.

Elife
|May 31, 2017
PubMed
Summary

Fruit flies

Area of Science:

  • Neuroscience
  • Chronobiology
  • Physiology

Background:

  • The fruit fly, *Drosophila melanogaster*, possesses a sophisticated thermoregulatory system.
  • Circadian rhythms, governed by the central clock, influence various physiological processes.
  • Integrating sensory information with internal timekeeping is crucial for organismal adaptation.

Purpose of the Study:

  • To investigate the interplay between temperature-sensing neurons and the circadian clock in *Drosophila*.
  • To elucidate the neural mechanisms underlying body temperature regulation in response to environmental temperature fluctuations.

Main Methods:

  • Utilized genetic manipulation to target specific temperature-sensing neurons.
  • Employed calcium imaging to monitor neuronal activity in response to temperature changes.
Keywords:
D. melanogasterDN2 neuronsPDF neuronsbody temperaturecircadian rhythmsneurosciencetemperature preference behaviorthermosensory neurons

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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

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Related Experiment Videos

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  • Assessed the impact of circadian clock disruption on thermoregulatory behavior.

    • Main Results:

    • Identified specific temperature-sensing neurons that are modulated by the circadian clock.
    • Demonstrated that these neurons exhibit altered activity patterns under different thermal conditions and circadian states.
    • Showed that disrupting the circadian clock impairs the fly's ability to maintain a stable body temperature.

    Conclusions:

    • Temperature-sensing neurons and the central circadian clock in *Drosophila* are functionally integrated.
    • This cooperation is essential for precise body temperature regulation in response to environmental cues.
    • Provides a foundation for understanding conserved mechanisms of neuro-circadian-thermal integration.