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A 9-Day-Old With Weight Loss and Diarrhea

Prabi Rajbhandari1,2, Chetan Mandelia2, Halima S Janjua2

  • 1Akron Children's Hospital, Akron, Ohio; and prajbhandari@chmca.org.

Pediatrics
|May 31, 2017
PubMed

Insights

This case study details a 9-day-old infant with severe hypernatremia, hyperkalemia, and acute kidney injury. The infant presented with diarrhea and weight loss, highlighting a rare pediatric presentation.

Area of Science:

  • Pediatric Nephrology
  • Neonatal Intensive Care
  • Clinical Case Study

Background:

  • A 9-day-old infant presented with significant weight loss and watery diarrhea.
  • Family history was notable for hypertrophic cardiomyopathy.

Observation:

  • Infant experienced nonmucoid watery stools 5-15 times daily.
  • Initial assessment revealed normal vital signs and physical examination.
  • Laboratory findings included hypernatremia, hyperkalemia, metabolic acidosis, and acute kidney injury.

Findings:

  • Hypernatremia was resistant to standard fluid management strategies.
  • The clinical presentation suggested a complex electrolyte and renal disorder in a neonate.

Implications:

  • This case underscores the importance of considering rare diagnoses in neonates with severe electrolyte disturbances.
  • Early recognition and management are crucial for improving outcomes in infants with similar presentations.
  • Further investigation into the underlying etiology of the infant's condition is warranted.

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