Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epiphytes, Parasites, and Carnivores02:40

Epiphytes, Parasites, and Carnivores

17.0K
Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the...
17.0K
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

3.3K
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
3.3K
Surface Appendages of Archaea01:23

Surface Appendages of Archaea

763
Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
763
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

4.9K
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
4.9K
Diversity of Protists I01:15

Diversity of Protists I

1.6K
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
1.6K
Diversity of Protists IV01:27

Diversity of Protists IV

1.5K
Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structures of folding intermediates on BAM show diverse substrates fold by a conserved mechanism.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Mechanism of membrane perforation in rotavirus cell entry.

bioRxiv : the preprint server for biology·2026
Same author

Structures of folding intermediates on BAM show diverse substrates fold by a uniform mechanism.

bioRxiv : the preprint server for biology·2025
Same author

A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores.

The Journal of cell biology·2025
Same author

Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases.

Vaccine·2025
Same author

Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases.

bioRxiv : the preprint server for biology·2025
Same journal

Ultrastructural evidence of autophagy-related processes and mitochondrial remodeling in the myxozoan parasite Henneguya piaractus.

Journal of structural biology·2026
Same journal

Architecture and dynamics of a supramolecular oxygen transport system in human homogentisate 1,2-Dioxygenase.

Journal of structural biology·2026
Same journal

Connecting pathways between mineralized fibrocartilage and bone at the Achilles tendon insertion.

Journal of structural biology·2026
Same journal

Structural and functional characterization of thermostable EstS1 esterase for BHET degradation.

Journal of structural biology·2026
Same journal

Following the white rabbit: multiscale 2D3D correlative imaging of bone structure.

Journal of structural biology·2026
Same journal

The mantis shrimp eye imaged in 3D using 4th generation synchrotron multiscale phase contrast tomography.

Journal of structural biology·2026
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
08:17

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

9.1K

Protein tentacles.

Stephen C Harrison1

  • 1Harvard Medical School, Boston Children's Hospital, and Howard Hughes Medical Institute, 250 Longwood Ave., Boston MA 02115, United States.

Journal of Structural Biology
|June 1, 2017
PubMed
Summary
This summary is machine-generated.

Protein assembly in viruses provides early models for molecular machines. This work introduces "tentacular interactions" as a key concept for understanding how these structures organize and are regulated.

Keywords:
Peptide-surface associationProtein interactionsRegulated assemblyVirus structure

More Related Videos

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research
09:10

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Published on: September 22, 2021

3.3K
Fluorescent In Situ Hybridization and 5-Ethynyl-2'-Deoxyuridine Labeling for Stem-Like Cells in the Hydrozoan Jellyfish Cladonema pacificum
08:44

Fluorescent In Situ Hybridization and 5-Ethynyl-2'-Deoxyuridine Labeling for Stem-Like Cells in the Hydrozoan Jellyfish Cladonema pacificum

Published on: August 3, 2022

3.6K

Related Experiment Videos

Last Updated: Mar 1, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
08:17

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

9.1K
Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research
09:10

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Published on: September 22, 2021

3.3K
Fluorescent In Situ Hybridization and 5-Ethynyl-2'-Deoxyuridine Labeling for Stem-Like Cells in the Hydrozoan Jellyfish Cladonema pacificum
08:44

Fluorescent In Situ Hybridization and 5-Ethynyl-2'-Deoxyuridine Labeling for Stem-Like Cells in the Hydrozoan Jellyfish Cladonema pacificum

Published on: August 3, 2022

3.6K

Area of Science:

  • Structural biology
  • Molecular biology
  • Biophysics

Background:

  • Virus structures revealed early principles of protein assembly.
  • Protein folding into complementary sites drives assembly.
  • Caspar's "tentacles" and "pentopuses" offer a conceptual framework.

Purpose of the Study:

  • To propose a new vocabulary for understanding molecular machines.
  • To highlight the role of "tentacular interactions" in protein assembly.
  • To explain the regulatory advantages of these interactions.

Main Methods:

  • Conceptual analysis based on virus structures.
  • Drawing analogies from existing biological metaphors (Caspar's work).
  • Literature review of protein assembly and regulation.

Main Results:

  • Introduction of "tentacular interactions" as a unifying concept.
  • Demonstration of this concept in virus assembly (SV40 pentamers).
  • Identification of regulatory advantages for assembly and disassembly.

Conclusions:

  • "Tentacular interactions" are fundamental to organizing most subcellular molecular machines.
  • This interaction model facilitates regulation by enzymes and chaperones.
  • The proposed vocabulary aids in understanding complex protein assemblies.