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Origin, evolution and dissemination of antibiotic resistance genes
P Trieu-Cuot1, M Arthur, P Courvalin
1Unité des Agents Antibactériens, Centre National de la Recherche Scientifique U.A. 271, Institut Pasteur, Paris, France.
Microbiological Sciences
|September 1, 1987
Abstract:
Comparison of resistance genes from different sources support the hypothesis that the antibiotic-producing microorganisms are the source of resistant determinants present in clinical isolates. There is also evidence that Gram-positive cocci (staphylococci and streptococci) can serve as a reservoir of resistance genes for Gram-negative bacteria.