Related Experiment Video
Updated: Mar 1, 2026

In Vitro Assay to Study Tumor-macrophage Interaction
Published on: August 1, 2019
Cytomegalovirus, Macrophages and Breast Cancer
S Pasquereau1, F Al Moussawi1, W Karam2
1Pathogens & Inflammation/EPILAB Laboratory, Department of Virology, University of Franche-Comté, COMUE Bourgogne Franche-Comté University, UPRES EA4266, SFR FED 4234, CHRU Besançon, Besançon, France.
Abstract:
The human cytomegalovirus (HCMV) is a betaherpesvirus that is highly host specific, infects among others epithelial cells and macrophages, and has been recently mentioned as having oncomodulatory properties. HCMV is detected in the breast tumor tissue where macrophages, especially tumor associated macrophages, are associated with a poor prognosis. In this review, we will discuss the potential implication of HCMV in breast cancer with emphasis on the role played by macrophages.

