Related Experiment Video
Updated: Mar 1, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
Malignization of a vestibular schwannoma 13 years after radiation therapy
S Simmermacher1, D Vordermark2, T Kegel3
1Klinik für Neurochirurgie, University Hospital Halle, Ernst-Grube-Straße 40, 06120, Halle, Germany. sebastian.simmermacher@uk-halle.de.
Abstract:
This article presents a case of malignant transformation of vestibular schwannoma 13 years after stereotactic radiation therapy, which lead to an acute life-threatening condition. Although the observation is currently only based on case reports, an increasing number of these support the hypothesis that there is a relevant risk of malignant transformation in the long-term course of previously irradiated vestibular schwannomas. Therefore, long-term MRI follow-up should be considered.

