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Updated: Mar 1, 2026

Selected Reaction Monitoring Mass Spectrometry for Absolute Protein Quantification
Published on: August 17, 2015
Quantitative proteomics: challenges and opportunities in basic and applied research
Olga T Schubert1, Hannes L Röst2, Ben C Collins3
1Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, USA.
Abstract:
In this Perspective, we discuss developments in mass-spectrometry-based proteomic technology over the past decade from the viewpoint of our laboratory. We also reflect on existing challenges and limitations, and explore the current and future roles of quantitative proteomics in molecular systems biology, clinical research and personalized medicine.
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